Peptides/Tesofensine
⚖️ Weight Loss & Body Composition PRO

Tesofensine (NS2330 · TE)

Oral triple reuptake inhibitor with strong appetite-suppressing effect

Also known as:
NS2330TE

What is Tesofensine

Tesofensine is an oral inhibitor of norepinephrine, dopamine, and serotonin reuptake that reduces appetite and increases satiety through central action. Originally investigated for neurodegenerative diseases, it demonstrated in a phase II study (published in The Lancet, 2008) weight loss of approximately 10% over 24 weeks, roughly double that of other agents of the time.

Administration Protocol

PRO
1
Starting dose
0.25 mg per day
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Community reviews

4.0(3)
Marcos M.

Efeito mais sutil no meu caso, mas pode ser questão de tempo de uso. O material do site é honesto sobre isso.

11 de mai. de 2026
Rodrigo S.

Uso há algumas semanas e os resultados começaram a aparecer. Protocolo bem explicado aqui no site, ajudou muito.

05 de mai. de 2026
Renata A.

Funciona, mas exige consistência. As informações de armazenamento e reconstituição foram essenciais pra mim.

28 de jan. de 2026

Side effects

  • May cause dry mouth, insomnia, agitation, constipation, and elevated blood pressure and heart rate. Cardiovascular and mood effects require monitoring.

Contraindications

  • Contraindicated in uncontrolled hypertension, arrhythmias, significant cardiovascular disease, and severe psychiatric disorders. Do not combine with other serotonergic agents due to the risk of serotonin syndrome.

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Where to buy

Tesofensine from Royal Peptides — lab-tested purity and worldwide shipping.

View on Royal Peptides

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Quick Facts

ClassificationNorepinephrine, dopamine, and serotonin reuptake inhibitor
Half-life~8 days
CategoryWeight Loss & Body Composition
Evidence LevelClinical trials phase II

This content is informational. Consult a healthcare professional before using any peptide.